Cheapskate's step-by-step guide to create methaqualone (quaalude) from earth, wind, fire and water the following document is the results of my research into quaalude synthesis for the masses in the never ending war on the war on drugs, i consider this a major victory. Bromination of 4-methyl propiophenone to 4-methyl-2-bromopropiophenone, then reflux in methylamine to make 4-methyl methcathinone hive synthesis can be found by googling kinetic mephedrone synthesis. Hello again from your neighborhood drug author, for those unaware, i am currently writing a textbook on the synthesis/extraction of many drugs.
Synthesis mephedrone can be synthesised in several ways the simplest method, due to the availability of the compounds,: 17 is to add 4-methylpropiophenone dissolved in glacial acetic acid to bromine, creating an oil fraction of 4'-methyl-2-bromopropiophenone. Cathinone (figure 1) and its derivatives are closely related to the phenethylamine family thus cathinone itself is β-keto (βk) amphetamine, 2-aminopropiophenone or, more formally, 2-amino-1-phenyl-1-propanone (iupac systematic name.
In 2010, unconfirmed reports speculated about the role mephedrone has played in the deaths of several young people in the uk by july 2010, mephedrone had been alleged to be involved in 52 fatalities in the uk, but detected in only 38 of these cases.
248 ey santali et al / journal of pharmaceutical and biomedical analysis 56 (2011) 246–255 (2 ml), treated with hydrobromic acid (33% solution in acetic acid, 5ml) and stirred at room temperature for 1h. Journal of pharmaceutical and biomedical analysis 56 (2011) 246–255 contents lists available at sciencedirect journal of pharmaceutical and biomedical analysis.
The synthesis of methedrone is described in figure 1 and can be written as the following steps bromination of 1-(4-methoxyphenyl)propan-1-one to 2-bromo-1-(4-methoxyphenyl)propan-1-one a reaction with methylamine in which the 2-bromo-1-(4-methoxyphenyl)propan-1-one becomes 1-(4-methoxyphenyl)-2-(methylamino)propan-1-ol. Methylone synthesis (rated as: good read) do any bees know where a synthesis might be found for methylone, 2-methylamino-1-(3,4-methylenedioxypheny l)propan-1-one there are some journal entries regarding it's effects which are, in thses articles it states that the methylone was synthed, but does not indicate what the synthesis proceedure is. Synthesis of (±)-4′-methylmethcathinone hydrobromide [(±)-mephedrone hydrobromide] (3b) the title compound was prepared using an analogous method for ( 3a ) with the following modifications: the yellow oil, (±)-4′-methylmethcathinone, was dissolved in glacial acetic acid (2 ml), treated with hydrobromic acid (33% solution in acetic acid, 5 ml) and stirred at room temperature for 1 h. Mephedrone is metabolized by a number of pathways to the following metabolites: nor-mephedrone, nor-dihydro mephedrone, nor-hydroxytolyl mephedrone, 4-carboxy-dihydro mephedrone, hydroxytolyl mephedrone.
4-methylmethcathinone (also known as 4-mmc, m-cat, drone, meow meow, and mephedrone) is a novel entactogen-stimulant substance of the cathinone class mephedrone belongs to a group known as the substituted cathinone, which are derivatives of the active ingredient in the khat plant (catha edulluis. Mephedrone, also known as 4-methylmethcathinone (4-mmc), or 4-methylephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes slang names include meph, drone, mcat, meow meow, and bubble.
Mephedrone (hydrochloride) (item no 10801) is a designer drug that is structurally related to the psychotropic compound ecstasy (3,4-methylenedioxymethamphetamine) 1,2,3 nor-mephedrone (hydrochloride) (item no 9000940) is a metabolite of mephedrone that is formed by the n-demethylation of the primary amine on mephedrone 4,5 this metabolite. Synthesis of mephedrone is very simple to make no need for laboratory equipment and all the ingredients are legal and easily accessible (of course i include informations where is best place to buy them) i will answer any questions (please write on email [email protected] Synthesis of (±)-4′-methylmethcathinone hydrochloride [(±)-mephedrone hydrochloride] (3a) the title compound was prepared using the method reported by camilleri et al  with the following modifications: to a suspension of (±)-4′-methyl-2-bromopropiophenone (454 g, 20 mmol) and methylamine hydrochloride (135 g, 20 mmol) in dichloromethane (40 ml) was added triethylamine (558 ml, 40 mmol.